Gene search

Sequence information

Select Gene Cds Cds_length GC_content Pep Pep_length
Clacu05g0176 ATGGCGGTTGTGAGTGCTATGCTAGCAACTACACCTCGAGCTGGTCCAATTAATTATGCTGAAGCTTCACCAATTATGATCAGCTCAAGCAGAGAGATTGTGGAAGAGCCTGTGGGAGCTATTAGTGAAGATGTAATTTGTGTTGCTGTTGGGAAAGATGTGAAAGAGTGCTTATCAGTTTTGAGATATGCACTAAAATCCTCAGGTGGGAAGAAGATTTGCCTCCTACATATTCATGTCCCCGCACAGATGATTCCATTAATGGGAACCAAGTTTCCAGCAAACTCATTGGAGAAAGAGGAGGTGAGAGCATATCATGAGTTCGAGAAGCAAAATCTGCCGAGGGTCATGAATGAGTATATTCTATACTGTCTTCAAGAAGGGGTTCGTGCCGATAAATTATGTGCTGAAGCTGAGTGTATTGAAAAGGGAATAGTTGATATGATTTCCCTGCACAGGATAAATAAGCTCGTTATGGGAGCAGCTGTAGACAAGAGTTATTCAAGGAGAATGGTGGATCTGAAGTCTAAGAAAGCCATTTACGTGCGTTCACAGGCACCGGCTTTCTGTCACATTGACTTTATTTGCAAGGGGAACCTCATCTGCACCAGGGAGGGTAGATCAGATGGAGCTCAAGTAGAAACCGTCATCTCATCACCACAAACAAGTCCAGACGCTGAATCCTCAGAAACTACCCACTGGAGATCTCAGTCACTGCCACTTGAACAGTTTAATAGCAGGGAAGTCGGAACTCCTTCCAATGTACGTCCTAGAGGGAGATCATTGCTTTTTGACCATTTTAGAGGGAGCACACTAGATCCTTCTTCTCCAGATATTATGAGTGGGGTTCATACTGCAAGAAACTTGGATGTTAACGAGGCTATGGGTGAATGGGGTTTATTAACAAGGAGAAGTCCTTCTGAAAGGTCAGACAATTCCATACGCTCTCCTCGTGGTGTGATTGATATGGCTCCGTCCCCACTTTCTAGGGTTGAGTTATGTGCAAATAGGCCGGAGGATGGGAAGACCAGTGATTGCCTTTACAATCAATGTGAACGGGTGATGATGGAGGCTGCAAATGCAAGGCGCGAAGCATTTTTAGAGGCAATTGCGCGCAGAAAATCTGAGAAAGAAACTGTTAATGCTCTACACAGGGTTAGAGCTGCAGAAGGGTTATATGCTGAAGAACTGAAACAAAGGAAGGAGGTTGAACAAGAGCTAGCGAAGGAAAAGGAAAAACTTGAAAGTATAAAGGCACAACTAAATGAACAGATGGAAGAACTCCGGATAGCCCAAGATCAGAAGGCAAGTCTAGAGAGAGATCTTTTAGAATCTGATCTAACCGCAAAGGAGTTGGAGCAAAAGATTCTTTCTGCTGTTGAATTGTTACAGAGTTACAAAAGAGAGCGAGAGGAGTTGCAGATACAACGCGACAATGCACTTAGAGAAGCAGAGGAGCTTAGAAAAAATCAATCCACAGGCCAATACCTTCCGCAGTTCTTTACTGAGTTCCCTTTTCGGGAGATCGAGGAAGCAACTAAAAACTTTGATCCCTTCCTGAAGATTGGAGAAGGGGGATATGGAAGTATATTCCGAGGTAACTTGCGTCATACTATGGTGGCTATAAAAATTCTACATTCTGATAGCTCTCAAGGCCCCTCTGAATTTCAACAAGAGGTTAATGTATTGAGTAAGATGAGACATCCCAATCTTGTCACGCTCATTGGTGCCTGTCCTGAAGCTTGGGTTCTCATCTACGAATACCTCTCTAATGGAAGCCTCGAAGATAGGTTAAGCTGCAAGGATAATACTCCACCTTTATCTTGGCAAACACGAATACGTATCGCTACCGAGTTATGCTCGGCCCTTATGTTTCTTCACTCAAGTAAGCCCCACAGCATCATTCATGGTGACTTGAAACCTGCAAATGTATTACTTGATGCAAATTTTGTATGCAAGCTTGGAGACTTTGGAATTTGTCGCTTATTGTCTCGGGGTGAAATGCTAAACAACGAAACACTTGTTTGGAGAACTGACAACCCCAAGGGGACTTTTGCTTACATGGATCCTGAATTCCTTTCATCTGGAGAGCTAACAACAAAGTCAGATGTTTATTCATTCGGGATAATACTTTTGCGGTTATTGACTGGTAGATCTGCAATGGGGATATCAAAGGAAGTGCAATATGCAATGGCAAATGGAAAGTTAGAATCCATTTTGGATCCTTTAGCAGGAGATTGGCCGTTCGTGCAGGCTGAACAGATCGCTCGATTGGCATTGAGGTGTTGTGATATGAAGCGAAAGAGCCGCCCCGATCTCATTACTGATGTCTGGAGGGTGCTTGGACCAATGAGAGCTTCCTGTGGTGGCCTATTGTCCGTCCAGCTCGGTTCTGCAGAACACTCACATCCTCCCCCTTATTTTATCTGTCCCATCTTCCAGGAAGTCATGCAAGATCCACATGTAGCTGCAGATGGTTTTACATATGAAGCGGAGGCTGTGAGGGGATGGCTAGACAGTGGACACGATACTTCACCAATGACAAATCTTAGGCTCGAGCACCGCAACCTCGTCCCAAACCGTGCTCTTCGTTCTGCTATCCAAGAGTGGCTCCAACGGAACTGA 2625 44.5 MAVVSAMLATTPRAGPINYAEASPIMISSSREIVEEPVGAISEDVICVAVGKDVKECLSVLRYALKSSGGKKICLLHIHVPAQMIPLMGTKFPANSLEKEEVRAYHEFEKQNLPRVMNEYILYCLQEGVRADKLCAEAECIEKGIVDMISLHRINKLVMGAAVDKSYSRRMVDLKSKKAIYVRSQAPAFCHIDFICKGNLICTREGRSDGAQVETVISSPQTSPDAESSETTHWRSQSLPLEQFNSREVGTPSNVRPRGRSLLFDHFRGSTLDPSSPDIMSGVHTARNLDVNEAMGEWGLLTRRSPSERSDNSIRSPRGVIDMAPSPLSRVELCANRPEDGKTSDCLYNQCERVMMEAANARREAFLEAIARRKSEKETVNALHRVRAAEGLYAEELKQRKEVEQELAKEKEKLESIKAQLNEQMEELRIAQDQKASLERDLLESDLTAKELEQKILSAVELLQSYKREREELQIQRDNALREAEELRKNQSTGQYLPQFFTEFPFREIEEATKNFDPFLKIGEGGYGSIFRGNLRHTMVAIKILHSDSSQGPSEFQQEVNVLSKMRHPNLVTLIGACPEAWVLIYEYLSNGSLEDRLSCKDNTPPLSWQTRIRIATELCSALMFLHSSKPHSIIHGDLKPANVLLDANFVCKLGDFGICRLLSRGEMLNNETLVWRTDNPKGTFAYMDPEFLSSGELTTKSDVYSFGIILLRLLTGRSAMGISKEVQYAMANGKLESILDPLAGDWPFVQAEQIARLALRCCDMKRKSRPDLITDVWRVLGPMRASCGGLLSVQLGSAEHSHPPPYFICPIFQEVMQDPHVAADGFTYEAEAVRGWLDSGHDTSPMTNLRLEHRNLVPNRALRSAIQEWLQRN 874
       

Gff information

Chromosome Start End Strand Old_gene Gene Num
5 1621548 1626458 - ClG42_05g0017600.10 Clacu05g0176 247923

Annotation

Select Seq ID Length Analysis Description Start End IPR GO
Clacu05g0176 874 SMART serkin_6 516 781 IPR000719 GO:0004672(InterPro)|GO:0005524(InterPro)|GO:0006468(InterPro)
Clacu05g0176 874 SUPERFAMILY RING/U-box 799 874 - -
Clacu05g0176 874 Gene3D Transferase(Phosphotransferase) domain 1 589 787 - -
Clacu05g0176 874 ProSiteProfiles U-box domain profile. 803 874 IPR003613 GO:0004842(InterPro)|GO:0016567(InterPro)
Clacu05g0176 874 SMART Ubox_2 807 870 IPR003613 GO:0004842(InterPro)|GO:0016567(InterPro)
Clacu05g0176 874 Pfam U-box domain 805 874 IPR003613 GO:0004842(InterPro)|GO:0016567(InterPro)
Clacu05g0176 874 MobiDBLite consensus disorder prediction 216 252 - -
Clacu05g0176 874 MobiDBLite consensus disorder prediction 216 257 - -
Clacu05g0176 874 ProSiteProfiles Protein kinase domain profile. 516 808 IPR000719 GO:0004672(InterPro)|GO:0005524(InterPro)|GO:0006468(InterPro)
Clacu05g0176 874 ProSitePatterns Protein kinases ATP-binding region signature. 522 543 IPR017441 GO:0005524(InterPro)
Clacu05g0176 874 ProSitePatterns Serine/Threonine protein kinases active-site signature. 634 646 IPR008271 GO:0004672(InterPro)|GO:0006468(InterPro)
Clacu05g0176 874 SUPERFAMILY Protein kinase-like (PK-like) 490 773 IPR011009 -
Clacu05g0176 874 Gene3D Phosphorylase Kinase; domain 1 496 588 - -
Clacu05g0176 874 CDD STK_N 45 198 - -
Clacu05g0176 874 Pfam Protein kinase domain 521 772 IPR000719 GO:0004672(InterPro)|GO:0005524(InterPro)|GO:0006468(InterPro)
Clacu05g0176 874 Coils Coil 386 490 - -
Clacu05g0176 874 CDD RING-Ubox_WDSUB1-like 805 860 - -
Clacu05g0176 874 PANTHER OS02G0152300 PROTEIN 47 868 IPR051348 -
Clacu05g0176 874 Gene3D Zinc/RING finger domain, C3HC4 (zinc finger) 802 874 IPR013083 -
Clacu05g0176 874 FunFam Adenine nucleotide alpha hydrolase-like domain kinase 488 588 - -
       

Pathway

Select Query KO Definition Second KO KEGG Genes ID GHOSTX Score
Clacu05g0176 - - - - 0.0
       

Dupl-types

Select Gene1 Location1 Gene2 Location2 E-value Duplicated-type
Clacu01g1901 Clacu-Chr1:31135242 Clacu05g0176 Clacu-Chr5:1621548 3.40E-71 dispersed
Clacu02g2075 Clacu-Chr2:34005033 Clacu05g0176 Clacu-Chr5:1621548 2.90E-133 dispersed
Clacu05g0176 Clacu-Chr5:1621548 Clacu11g0311 Clacu-Chr11:2797434 7.10E-91 dispersed
Clacu05g0169 Clacu-Chr5:1557720 Clacu05g0176 Clacu-Chr5:1621548 1.70E-44 proximal
Clacu07g0204 Clacu-Chr7:2417510 Clacu05g0176 Clacu-Chr5:1621548 3.00E-06 transposed
Clacu11g0461 Clacu-Chr11:4379198 Clacu05g0176 Clacu-Chr5:1621548 8.20E-47 wgd
Clacu05g0176 Clacu-Chr5:1621548 Clacu05g0964 Clacu-Chr5:8539381 2.70E-151 wgd
Clacu05g0176 Clacu-Chr5:1621548 Clacu06g0365 Clacu-Chr6:4373222 2.70E-231 wgd
       

Syn-Families

Select Gene Event_type S_start S_end Function Ath_gene Identity(%) E-value Score
Clacu10g1529 . 1 1041 U-box Gene Family AT5G15400 76.0 0.0e+00 1577.0
Clacu02g1283 . 335 979 U-box Gene Family AT2G23140 66.5 1.2e-124 444.1
Clacu08g1877 . 1 780 U-box Gene Family AT1G24330 59.5 3.5e-243 838.2
Clacu11g1569 . 1 755 U-box Gene Family AT1G24330 58.3 2.6e-230 795.4
Clacu08g1877 . 1 779 U-box Gene Family AT1G67530 59.3 4.4e-241 831.2
Clacu11g1569 . 1 756 U-box Gene Family AT1G67530 57.3 2.3e-226 782.3
Clacu01g2318 . 1 362 U-box Gene Family AT4G21350 62.1 2.4e-120 429.1
Clacu07g0205 . 135 455 U-box Gene Family AT3G07360 54.6 1.2e-78 290.4
Clacu07g0636 . 265 452 U-box Gene Family AT1G71020 70.9 8.2e-73 271.6
Clacu01g0615 . 1073 1272 U-box Gene Family AT1G71020 55.9 2.9e-54 209.9
Clacu03g0161 . 281 450 U-box Gene Family AT1G71020 57.8 9.1e-48 188.3
Clacu05g2310 . 249 414 U-box Gene Family AT1G71020 57.4 5.9e-47 185.7
Clacu02g2083 . 255 425 U-box Gene Family AT1G71020 57.6 1.0e-46 184.9
Clacu07g0636 . 16 656 U-box Gene Family AT1G23030 56.6 6.3e-110 395.2
Clacu01g0615 . 859 1462 U-box Gene Family AT1G23030 52.4 8.3e-86 315.1
Clacu03g0161 . 116 655 U-box Gene Family AT2G28830 59.9 2.7e-102 369.8
Clacu02g2083 . 93 635 U-box Gene Family AT2G28830 50.8 1.2e-99 360.9
Clacu03g0161 . 24 689 U-box Gene Family AT3G46510 68.2 3.4e-170 595.5
Clacu02g2083 . 3 638 U-box Gene Family AT3G46510 66.3 5.6e-157 551.6
Clacu05g2310 . 16 623 U-box Gene Family AT3G46510 58.6 5.0e-121 432.2
Clacu02g1019 . 36 640 U-box Gene Family AT3G46510 50.2 6.2e-87 318.9
Clacu05g2310 . 12 625 U-box Gene Family AT3G54850 68.3 8.6e-163 570.9
Clacu02g2083 . 13 628 U-box Gene Family AT3G54850 57.3 2.3e-115 413.3
Clacu03g0161 . 31 650 U-box Gene Family AT3G54850 55.9 1.8e-104 377.1
Clacu02g1019 . 92 644 U-box Gene Family AT5G42340 64.2 7.2e-128 454.9
Clacu04g0698 . 9 669 U-box Gene Family AT5G01830 57.4 1.4e-198 689.9
Clacu03g0744 . 1 713 U-box Gene Family AT1G29340 67.9 1.4e-246 849.4
Clacu05g1286 . 27 442 U-box Gene Family AT5G37490 51.7 1.2e-110 397.1
Clacu04g0556 . 4 422 U-box Gene Family AT3G52450 52.4 3.1e-119 425.6
Clacu10g1808 . 1 403 U-box Gene Family AT3G52450 50.7 2.3e-114 409.5
Clacu10g1808 . 1 403 U-box Gene Family AT2G35930 55.6 4.5e-120 428.3
Clacu04g0556 . 7 422 U-box Gene Family AT2G35930 51.4 3.6e-117 418.7
Clacu05g1171 . 9 426 U-box Gene Family AT3G19380 64.1 3.4e-147 518.5
Clacu05g1171 . 1 426 U-box Gene Family AT1G49780 64.3 1.0e-151 533.5
Clacu01g1622 . 1 407 U-box Gene Family AT5G64660 54.2 2.4e-121 432.6
Clacu01g1622 . 1 407 U-box Gene Family AT5G09800 51.3 6.3e-106 381.3
Clacu08g1825 . 1 454 U-box Gene Family AT3G49810 63.0 3.0e-154 542.0
Clacu05g2866 . 1 454 U-box Gene Family AT3G49810 62.6 2.0e-153 539.3
Clacu08g1825 . 1 454 U-box Gene Family AT5G65920 63.9 1.5e-153 539.7
Clacu05g2866 . 1 454 U-box Gene Family AT5G65920 61.3 2.7e-147 518.8
Clacu05g0176 . 1 872 U-box Gene Family AT2G45910 53.0 3.8e-235 811.6
Clacu11g0311 . 4 725 U-box Gene Family AT2G19410 50.1 2.2e-208 722.6
Clacu01g0471 . 65 841 U-box Gene Family AT4G25160 51.7 3.3e-218 755.4
Clacu06g1777 . 1 478 U-box Gene Family AT5G65200 50.1 2.8e-88 323.2
Clacu09g1914 . 1 551 U-box Gene Family AT5G40140 53.9 1.5e-94 344.0
Clacu06g1777 . 27 477 U-box Gene Family AT5G40140 51.5 2.0e-59 227.3
Clacu01g1482 . 29 498 U-box Gene Family AT5G40140 52.1 2.7e-56 216.9
Clacu08g1090 . 26 834 U-box Gene Family AT1G76390 61.2 5.1e-269 924.1
Clacu08g1090 . 35 834 U-box Gene Family AT1G20780 61.7 2.1e-278 955.3
Clacu08g1877 . 1 782 U-box Gene Family AT1G27910 62.5 2.7e-267 918.3
Clacu11g1569 . 1 767 U-box Gene Family AT1G27910 62.4 4.0e-263 904.4
Clacu01g1826 . 444 1035 U-box Gene Family AT5G67530 74.0 3.2e-260 894.4
Clacu05g0243 . 656 813 U-box Gene Family AT5G67530 52.5 3.1e-45 180.3
Clacu10g1853 . 12 162 U-box Gene Family AT5G67530 50.3 9.3e-42 168.7
Clacu05g0448 . 1 517 U-box Gene Family AT1G04510 74.2 6.8e-222 766.9
Clacu05g0448 . 1 486 U-box Gene Family AT2G33340 73.4 6.1e-209 723.8
Clacu07g0204 . 10 278 U-box Gene Family AT3G07370 66.9 2.9e-102 368.6
Clacu10g1529 . 1 1041 U-box Gene Family AT5G15400 76.0 0.0e+00 1577.0
Clacu02g1283 . 335 979 U-box Gene Family AT2G23140 66.5 1.2e-124 444.1
Clacu08g1877 . 1 780 U-box Gene Family AT1G24330 59.5 3.5e-243 838.2
Clacu11g1569 . 1 755 U-box Gene Family AT1G24330 58.3 2.6e-230 795.4
Clacu08g1877 . 1 779 U-box Gene Family AT1G67530 59.3 4.4e-241 831.2
Clacu11g1569 . 1 756 U-box Gene Family AT1G67530 57.3 2.3e-226 782.3
Clacu01g2318 . 1 362 U-box Gene Family AT4G21350 62.1 2.4e-120 429.1
Clacu07g0205 . 135 455 U-box Gene Family AT3G07360 54.6 1.2e-78 290.4
Clacu07g0636 . 265 452 U-box Gene Family AT1G71020 70.9 8.2e-73 271.6
Clacu01g0615 . 1073 1272 U-box Gene Family AT1G71020 55.9 2.9e-54 209.9
Clacu03g0161 . 281 450 U-box Gene Family AT1G71020 57.8 9.1e-48 188.3
Clacu05g2310 . 249 414 U-box Gene Family AT1G71020 57.4 5.9e-47 185.7
Clacu02g2083 . 255 425 U-box Gene Family AT1G71020 57.6 1.0e-46 184.9
Clacu07g0636 . 16 656 U-box Gene Family AT1G23030 56.6 6.3e-110 395.2
Clacu01g0615 . 859 1462 U-box Gene Family AT1G23030 52.4 8.3e-86 315.1
Clacu03g0161 . 116 655 U-box Gene Family AT2G28830 59.9 2.7e-102 369.8
Clacu02g2083 . 93 635 U-box Gene Family AT2G28830 50.8 1.2e-99 360.9
Clacu03g0161 . 24 689 U-box Gene Family AT3G46510 68.2 3.4e-170 595.5
Clacu02g2083 . 3 638 U-box Gene Family AT3G46510 66.3 5.6e-157 551.6
Clacu05g2310 . 16 623 U-box Gene Family AT3G46510 58.6 5.0e-121 432.2
Clacu02g1019 . 36 640 U-box Gene Family AT3G46510 50.2 6.2e-87 318.9
Clacu05g2310 . 12 625 U-box Gene Family AT3G54850 68.3 8.6e-163 570.9
Clacu02g2083 . 13 628 U-box Gene Family AT3G54850 57.3 2.3e-115 413.3
Clacu03g0161 . 31 650 U-box Gene Family AT3G54850 55.9 1.8e-104 377.1
Clacu02g1019 . 92 644 U-box Gene Family AT5G42340 64.2 7.2e-128 454.9
Clacu04g0698 . 9 669 U-box Gene Family AT5G01830 57.4 1.4e-198 689.9
Clacu03g0744 . 1 713 U-box Gene Family AT1G29340 67.9 1.4e-246 849.4
Clacu05g1286 . 27 442 U-box Gene Family AT5G37490 51.7 1.2e-110 397.1
Clacu04g0556 . 4 422 U-box Gene Family AT3G52450 52.4 3.1e-119 425.6
Clacu10g1808 . 1 403 U-box Gene Family AT3G52450 50.7 2.3e-114 409.5
Clacu10g1808 . 1 403 U-box Gene Family AT2G35930 55.6 4.5e-120 428.3
Clacu04g0556 . 7 422 U-box Gene Family AT2G35930 51.4 3.6e-117 418.7
Clacu05g1171 . 9 426 U-box Gene Family AT3G19380 64.1 3.4e-147 518.5
Clacu05g1171 . 1 426 U-box Gene Family AT1G49780 64.3 1.0e-151 533.5
Clacu01g1622 . 1 407 U-box Gene Family AT5G64660 54.2 2.4e-121 432.6
Clacu01g1622 . 1 407 U-box Gene Family AT5G09800 51.3 6.3e-106 381.3
Clacu08g1825 . 1 454 U-box Gene Family AT3G49810 63.0 3.0e-154 542.0
Clacu05g2866 . 1 454 U-box Gene Family AT3G49810 62.6 2.0e-153 539.3
Clacu08g1825 . 1 454 U-box Gene Family AT5G65920 63.9 1.5e-153 539.7
Clacu05g2866 . 1 454 U-box Gene Family AT5G65920 61.3 2.7e-147 518.8
Clacu05g0176 . 1 872 U-box Gene Family AT2G45910 53.0 3.8e-235 811.6
Clacu11g0311 . 4 725 U-box Gene Family AT2G19410 50.1 2.2e-208 722.6
Clacu01g0471 . 65 841 U-box Gene Family AT4G25160 51.7 3.3e-218 755.4
Clacu06g1777 . 1 478 U-box Gene Family AT5G65200 50.1 2.8e-88 323.2
Clacu09g1914 . 1 551 U-box Gene Family AT5G40140 53.9 1.5e-94 344.0
Clacu06g1777 . 27 477 U-box Gene Family AT5G40140 51.5 2.0e-59 227.3
Clacu01g1482 . 29 498 U-box Gene Family AT5G40140 52.1 2.7e-56 216.9
Clacu08g1090 . 26 834 U-box Gene Family AT1G76390 61.2 5.1e-269 924.1
Clacu08g1090 . 35 834 U-box Gene Family AT1G20780 61.7 2.1e-278 955.3
Clacu08g1877 . 1 782 U-box Gene Family AT1G27910 62.5 2.7e-267 918.3
Clacu11g1569 . 1 767 U-box Gene Family AT1G27910 62.4 4.0e-263 904.4
Clacu01g1826 . 444 1035 U-box Gene Family AT5G67530 74.0 3.2e-260 894.4
Clacu05g0243 . 656 813 U-box Gene Family AT5G67530 52.5 3.1e-45 180.3
Clacu10g1853 . 12 162 U-box Gene Family AT5G67530 50.3 9.3e-42 168.7
Clacu05g0448 . 1 517 U-box Gene Family AT1G04510 74.2 6.8e-222 766.9
Clacu05g0448 . 1 486 U-box Gene Family AT2G33340 73.4 6.1e-209 723.8
Clacu07g0204 . 10 278 U-box Gene Family AT3G07370 66.9 2.9e-102 368.6
       

Syn-Orthogroups

Select Orthogroup Bda Bhi Blo Bma Bpe Cam Car Cco Cec Chy Cla Clacu Cma Cme Cmetu Cmo Cmu Cone Cpe Cre Csa HCH Hepe Lac Lcy Lsi Mch Sed Tan Vvi Total
OG0001926 1 4 1 0 1 0 3 1 1 2 2 1 3 2 1 3 1 0 3 1 2 3 3 1 2 2 3 4 2 1 54
       

Regulatory proteins

Select Gene Hmm_acc Hmm_name Score E-value Regulatory Factors Family
73533 PF00069 Pkinase 3.20E-42 CL0016 Clacu PK